Trained at the Academy of Fine Arts of Brera practiced in the early years in the historical compositions required by the teaching neoclassical canon. Starting from 1832 he began to exhibit a new type of humorous and satirical paintings – “a way of his own,” noted the artistic literature of the time – that met with some success (among other A poor beggar who is visiting her son to the doctor or some morra players).
This usually led him to debut at the Paris Salon of 1846 with La rixe de mendiants and assassinat The nocturne, where he found support in the pen of Charles Baudelaire who appreciated the extravagance neofiamminga. In 1854 Manzoni decided to move to Argentina where he installed a studio specialized in painting historical and religious not disdaining even painting still-lifes or bodegones. He returned to Italy only a few years after his death bringing one of his best known works: Mode of cooking the meat in the countryside of Buenos Aires exposed in 1877.